Subsys spray is a powerful and addictive painkiller for cancer. Taken as an oral spray, it is considered as one of the most potent and dangerous opioids at about 80 – 100 times stronger than morphine. Because it is sprayed underneath the tongue, it gets into the bloodstream faster than traditional methods of delivery. It is used for the treatment of chronic pain.
Insys Therapeutics, the manufacturer of Subsys or Fentanyl Spray is currently under investigation for off-label prescription of fentanyl. Subys is approved by the FDA for breakthrough cancer pain. The drug was allegedly prescribed for conditions which Fentanyl was not approved for. According to reports, it was prescribed for joint pain and post-traumatic stress disorder. The manufacturer of the drug allegedly falsified records so the drug can be taken by non-cancer patients.
Introduced in 2012, the Adverse Events Reporting System of the FDA has listed around 203 deaths with Subsys listed as being the probable cause for triggering an adverse reaction. In the second quarter of 2015 alone, the number of fentanyl related deaths was 52. Insys is now under Federal and state investigations in Oregon, California, Massachusetts, Connecticut, Arizona, and Illinois. To date, the company has already settled a total of $7.2 million in class action suit in Oregon and Arizona.
The website of Williams Kherkher revealed that the sales of Insys increased to more than $90 million in the third quarter of 2015 alone despite the cost of hundreds of overdose deaths, lost loved ones, and ruined lives. The dangers of fentanyl became known to the public after reports of serious side effects and deaths linked to Duragesic pain patch or Fentanyl patches were issued. Overdose of the drug caused respiratory failure, permanent coma, and death. Due to these problems, the patches have been subjected to numerous recalls.
Having your license suspended can cause a lot of inconvenience on your part. For one, you are limited to the number of places where you can go. Aside from that, you would want to be very careful not to violate any traffic rules or you could find yourself in a much deeper hole. When your license is suspended, you may be limited with the number of things you can do with your car.
Depending on your violation, it is the Department of Motor Vehicle that determines how your license will be reinstated based on how it was suspended. Each violation will have different reinstate requirements. When your license was suspended, you might be required to obtain an SR-22 form. Your state’s Department of Motor Vehicles will notify you of the suspension of your license through mail. Likewise, you can check the status of your license on your driving record.
On your driving record, you will find the following information: 1) the reason for the suspension of your license; 2) the duration of suspension, based on the severity of violation, and whether you are a repeat offender; 3) special requirements you need to satisfy
If your license was suspended outside of your home state, it will be sent back to your home state under the Interstate Driver’s License Compact, which honors the license suspension law of another state even though the violation was not committed in your state of residence. Under the agreement, you can appeal for the suspension in accordance with the laws in your state.
If the reason for the suspension was due to a post-conviction or post-arrest DUI, it is still possible to reinstate your driving privileges. You can file a petition through a separate civil proceeding to allow you to get a hardship or occupational driver’s license so you can continue working. With this license, you will still be given your driving privileges while your case is still pending.
Aside from employment, you may request for such license for bringing your kids to school, seeking medical attention, or taking care of a disabled family member. To apply, just file a petition and pay the corresponding fee to the clerk of court. However, the petition will not suffice for the restoration of your driving privileges. You must also request for a hearing and provide the prosecution team with the notice of hearing. During the hearing, you have to prove that you should be granted a hardship or occupational license.
In most states, you will be required to take the necessary steps to have your license reinstated. You need to pay a reinstatement fee or else your license will remain suspended.
Every relationship comes with its own set of problems and issues. While many couples are able to work through these problems on their own, individuals can often find themselves unable to properly deal with the issues in their relationship. When this becomes the case, many couples can find help through couples counseling. According to the website of The Solace Center, counseling allows couples to identify problems that are inhibiting their relationship.
One of the most challenging aspects of any relationship is getting to know all the in-and-outs and your partner’s personality. However, when one individual does not understand the needs of their partner, issues can arise and arguing can become frequent. Through couples counseling, not only can couples become more in tune with their partner’s personality but can use this knowledge to better meet their needs and avoid and handle conflict appropriately. This can also help couples modify dysfunctional behavior in their relationship, such as insulting their partner during an argument, and explore the proper conflict resolution behaviors.
However, couples counseling can go beyond simply dealing with arguments. By getting to know your partner on a deeper and emotional level, you may be able to explore issues that are affecting your relationship that you were not even aware of. For example, if one partner was neglected emotionally as a child, they may inadvertently be hiding emotions from the other partner, causing unresolved issues and a weaker relationship. This can also lead to increased and healthier communication in a relationship overall. The benefits and advantages of couples counseling are countless, with many couples seeking therapy before problems arise. Through couples counseling, you and your partner will be able to build a stronger and more caring relationship.
Ammos propel bullets using an enormous amount of force. This force is enough to produce sound so loud that even a short period of exposure may cause hearing damage. As such, gun enthusiasts are always on the lookout for either the best hearing protection, or the most efficient gun suppressor. But is it really possible to completely silence a gun? You’ll find out below.
The sound of a gun comes mainly from three different sources. The first one is when the gun’s hammer strikes the firing pin as you pull the trigger, which creates a sharp, metallic sound. Although this is not as ear-crushing as the gunfire itself, it still contributes to the sound a gun makes during each shot.
As the firing pin strikes the back of a bullet, it hits a primer that triggers the powder propellant inside the bullet’s casing to quickly generate an enormous amount of hot gas. The hot gas creates immense pressure at the back of the bullet, usually at 3,000 pounds per square inch, which pushes the bullet down the barrel. As the gas expands, it creates a sound which can be as loud as 165 decibels, which may cause permanent ear damage.
The third sound is created when the bullet finally comes out of the barrel and whizzes past a target. It is called a bullet crack. A ballistic crack is so unique that it makes it possible for you to distinguish gunfire from booms created by fireworks, for instance.
Now, for the question, is it really possible to silence a gun altogether? Gun suppressors are only able to silence the second sound (the sound created by hot gasses). By making the barrel longer and wider, the hot gas has more room to dissipate, which decreases the sound the pressure creates. According to the website by Suppressed Weapon Systems, suppressors are available either as a separate piece of equipment which is threaded onto a firearm, or as a combination of a suppressor and a barrel.
A divorce is already a difficult situation. However, divorce proceedings can become even more challenging when there are children involved in the process. Divorcing parents will need to make several different decisions in regards to the well-being of their children. While some couples are able to come to an amicable agreement on their own, most will need the intervention of a mediator or a family court in order to come to a concession. Among the many decisions divorcing parents need to make is with regards to child custody and child support.
A child custody arrangement determines how each parent will be able to participate and figure in the life and caretaking of children after a marriage ends and a divorce is concluded. In most U.S. states, child custody arrangements can be classified into the following:
Determining a child support agreement is necessary for the last two scenarios where only one parent is considered the custodial parent. In these cases, the non-custodial parent is legally obligated to offer monthly financial assistance to the parent with physical custody of their children. The amount of the payment will depend on important factors that revolve around the best interest of the children involved. In particular, the court will look into the age and needs of the children involved in the custody battle, as well as the age, health, and income of each parent. A child support agreement settled by the court ensures that the custodial parent will not be able to deprive the non-custodial parent his or her right to visit and spend time with the children. On the other hand, the non-custodial parent will also be unable to escape or avoid his or her financial responsibility to their children. This is true even when the non-custodial parent is denied their rightful visitation time.
Considering this information, it’s easy to surmise that child support payments can quickly become a complicated issue. As such, it would be best to contact experienced family lawyers for more specific details that could help your own situation. As the Arenson Law Group, PC divorce lawyers put it on their website, having qualified legal counsel on your side can be a very valuable resource during a difficult child custody proceeding and it could make the difference on the outcome.
The National Highway Traffic Safety Administration (NHTSA) has never ceased in creating and implementing programs and designing educational campaigns that will continuously remind drivers of the necessity of observing road safety rules to keep accidents minor and at a minimum. This is because about three-fourths of the more than five million motor vehicle accidents in the US (every year) are due to driver’s faults, like speeding, reckless driving, drunk driving, which is the number one cause of car accidents, and distracted driving, which greatly involves teenage and young adult drivers. This, somehow, points to the alarming odds that, no matter how careful one may drive, if another driver acts negligently or carelessly, then an accident may just occur.
Drivers, however, are not the only ones guilty of acts of negligence, for there are also factors or other causes of accidents that are outside of drivers’ control. These include cars with manufacturing defects or low-quality car parts and defective roads and highways. Often, these other factors present greater dangers for these may not be immediately obvious, being discovered only after having caused tragic road mishaps.
The dangerous effects of a defectively-designed highway or a poorly-maintained street is definitely more extensive than car manufacturing defects as the former directly affects more (if not all) motorists. Highway defects include not enough or weakly constructed guardrails, traffic signs blocked by trees or other fixtures, poorly lighted streets, lack of railroad crossing lights and traffic lights, wrong road signs, uneven pavement, roadway debris, potholes, and so forth.
States, municipalities and cities are the ones responsible in the construction and maintenance of roads. States, however, has immunity from any form of liability (despite injuries during an accident), which is based on the rule that, so long as they follow approved construction plans, then they are exempt from paying any claims by an accident victim.
According to the website of Abel Law, the chance of a victim in winning the court’s approval to claim for damages, therefore, depends on the ability and competence of the personal injury lawyer, on whom rests the burden to prove that the risk of accident should have been foreseen or discovered by the state.
Because of the rising demand and popularity of medical spas, or medi-spas, there have been many who have taken advantage and set up their businesses even though they do not have proper licenses and training to perform such treatments and procedures. In order to ensure that you are going to a good and licensed medical spa, consider these tips:
Many doctors lend their names to medical spas in order to give more credence to the medical spa, although they may also aim to sell more services to their patients. Although you have been recommended a treatment, you still have to judge if you really need the treatment or not. Talk with your doctor or therapist regarding any question that bothers you about the treatment or procedure, and make sure to conduct your own research to determine if it really is the best choice for you.
First off, let us be clear about one thing: there is no such thing as SR-22 insurance. Standard car insurance refers to a policy agreement between an insurance company and the insured that when it becomes necessary, the insurance policy will pay for damages to or caused by the insured as covered under the policy. Minimum coverage amounts for specific types of insurance, typically liability, are required by law to operate a vehicle, and it is renewable every year.
On the other hand, an SR-22 is a certificate issued by an accredited insurance company to the appropriate government agency guaranteeing that a particular individual under special circumstances has the necessary insurance coverage for the prescribed time period. It is formally known as a certificate of financial responsibility. As such, it is not an insurance policy.
However, because it is a financial guarantee and issued by an insurance company, it is understandable why some people consider it as a form of car insurance, and why insurance companies cater to this belief. It eliminates the need for a long explanation, but it may be important for some people to understand what the SR-22 actually is.
The SR-22 is required in most states for some people under special circumstances. These include but not limited to driving without insurance, driving under the influence of drugs or alcohol, excessive number of moving violations, and involvement in a car accident when the individual is found to be at fault. In many cases, these drivers have their licenses suspended or revoked, or have difficulty in getting insurance coverage. In order to address these issues, some states require an SR-22 to either lift the suspension or revocation of a license to drive, or for an individual to legally drive in the state.
An SR-22 must be maintained over an effective period between 3 to 5 years, depending on what is appropriate for the circumstances. In this it is again distinct from standard car insurance, which one can cancel at any time without effect on their license (unless they operate a vehicle without getting alternate insurance coverage). If a person required an SR-22 avoids any incidents within the effective period, an SR-22 may no longer need to be renewed and the individual can acquire regular, and much less expensive, car insurance. For more information about car insurance, contact your local car accident lawyer.
For the past twenty years, a certain class of anti-depressant drugs has been the most common content of doctors’ prescriptions both within and outside the US. This class of medication is known as Selective serotonin reuptake inhibitors or SSRIs, and all specific drugs under it are highly reputed due to their effectiveness and safety.
SSRIs are said to increase the amount of serotonin or neurotransmitters, a chemical that is produced by the brain and which attaches themselves to other brain nerve receptors, altering a patient’s mood in the process.
SSRIs were specifically developed to treat major depressive disorder; however, these are also commonly prescribed to treat cases of anxiety disorders, including obsessive–compulsive disorder (OCD), panic disorders, chronic pain, social anxiety disorder, eating disorders and, sometimes, posttraumatic stress disorder (PTSD).
Besides blocking the “reuptake” or re-absorption of serotonin in the brain, SSRIs also do not affect other neurotransmitters, thus, the term “selective.” This selectivity is one of the therapeutic advantages of SSRIs over other antidepressant.
One specific type or SSRI medication is the generic drug Citalopram (with brand name Celexa). This oral antidepressant drug works by preventing neurotransmitters from being reabsorbed into the brain (after the brain has manufactured and released them), resulting to more of these chemical to stimulate the brain’s nerve cells.
Citalopram was primarily developed to treat depression; some doctors, however also prescribe it for off-label use (not among those approved by the US Food and Drug Administration) for treatment of panic disorder, anxiety disorder, obsessive compulsive disorder (OCD), posttraumatic stress disorder and premenstrual dysphoric syndrome or PMDD. Citalopram has also been known to be an effective treatment for patients with Generalized Anxiety Disorder (GAD).
Citalopram should never be used with non-steroidal anti-inflammatory drugs, aspirin or any other medication that affect bleedings as this may increase the risk of upper gastrointestinal bleeding. Complications may also result if taken by pregnant women of nursing mothers.
Some of those who take the drug may experience any of the following side-effects: sexual dysfunction; dry mouth; nausea; headache; vomiting, drowsiness; excessive sweating; tremor and inability to sleep. Stopping the intake of Citalopram, though, may, to some, result to withdrawal reactions, like dizziness, tiredness, irritability, tingling sensations, and vivid dreams.
Although fat transfer (also known as fat grafting) surgeries have been around for decades, lately, new science technologies have made them more effective.
Doctors will remove fat from unwanted areas on the patient, such as the thighs, stomach or arms, and inject them into more desired areas. Unlike other types of fillers, fat transfer allows for a completely natural treatment. Furthermore, fat transfers may be permanent when done correctly, whereas other dermal fillers may only last about a year.
The fat can be relocated into the buttocks, breasts, or face and hands for an anti-aging effect.
Fat injected into the face can often correct deep wrinkles and give the face a more youthful, fuller look. Many patients choose to group a face or brow lift with a fat transfer procedure in order to give the face a more overall youthful appearance.
Buttocks augmentation, also known as a “Brazilian butt lift” can be achieved to reshape the rear and give it a firmer, fuller shape. Fat is often taken from areas around the rear, such as the hips or the tops of the thighs to further accentuate the rear.
Fat transfer can even be used as a more natural alternative to the traditional “boob job”. For this procedure, like the others, liposuction is used to gather large amounts of fat needed to enlarge the breasts. It is then injected back into the chest. The results are often “softer” and more natural-looking than other types of breast augmentation.